Synthetic rat atrial natriuretic factor inhibits in vitro and in vivo renin secretion in rats.

K, Obana; M, Naruse; K, Naruse; H, Sakurai; H, Demura; T, Inagami; K, Shizume

doi:10.1210/endo-117-3-1282

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Synthetic rat atrial natriuretic factor inhibits in vitro and in vivo renin secretion in rats.

Shared by NobleBlocks on Sep 1, 1985 • 12:00 AM UTC

Authors:

Obana K

Naruse M

Naruse K

Abstract

We investigated the action of a synthetic rat atrial natriuretic factor (ANF) with 28 amino acids on renin secretion in rats. Renin release by kidney cortex slices was determined after 90 min of incubation at 37C. ANF inhibited basal renin release in a dose-related fashion. ANF also decreased cAMP r...

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