Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells

K.Y. Cheng, Kenneth; S.L. Lam, Karen; Wang, Yu; Huang, Yü; Carling, David; Wu, Donghai; Wong, Chi‐Wai; Xu, Aimin

doi:10.2337/db06-1580

Public

Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells

Published in Diabetes • Apr 30, 2007

Authors:

Kenneth K.Y. Cheng

Karen S.L. Lam

Yu Wang

Abstract

Adiponectin protects the vascular system partly through stimulation of endothelial nitric oxide (NO) production and endothelium-dependent vasodilation. The current study investigated the role of two recently identified adiponectin receptors, AdipoR1 and -R2, and their downstream effectors in mediati...

Subject

Adiponectin

Internal medicine

Adiponectin receptor 1

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!