Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes

I. Baruch, Dror; L. Pasloske, Britten; B. Singh, Hardeep; Bi, Xiahui; C., Xin; Feldman, Michaël; F. Taraschi, Theodore; J. Howard, Russell

doi:10.1016/0092-8674(95)90054-3

Public

Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes

Published in Cell • Jul 1, 1995

Authors:

Dror I. Baruch

Britten L. Pasloske

Hardeep B. Singh

Abstract

Plasmodium falciparum-infected human erythrocytes evade host immunity by expression of a cell-surface variant antigen and receptors for adherence to endothelial cells. These properties have been ascribed to P. falciparum erythrocyte membrane protein 1 (PfEMP1), an antigenically diverse malarial prot...

Subject

Biology

CD36

Plasmodium falciparum

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