Increased levels of ligands of Toll-like receptors 2 and 4 in type 1 diabetes

Devaraj, Sridevi; R. Dasu, Mohan; H. Park, S.; Jialal, Ishwarlal

doi:10.1007/s00125-009-1394-8

Public

Increased levels of ligands of Toll-like receptors 2 and 4 in type 1 diabetes

Published in Diabetologia • May 19, 2009

Authors:

Sridevi Devaraj

Mohan R. Dasu

S. H. Park

Abstract

AIMS/HYPOTHESIS: Type 1 diabetes is a proinflammatory state characterised by increased levels of circulating biomarkers of inflammation and monocyte activity. We have shown increased Toll-like receptor 2 (TLR2) and TLR4 expression and signalling in monocytes from type 1 diabetic patients. Several en...

Subject

TLR2

TLR4

Proinflammatory cytokine

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!