Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy

Sonza, Secondo; P. Mutimer, Helen; Oelrichs, Robert; Jardine, Darren; Harvey, Katya; Dunne, Amanda; F. J. Purcell, Damian; Birch, Christopher; M. Crowe, Suzanne

doi:10.1097/00002030-200101050-00005

Public

Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy

Published in AIDS • Jan 1, 2001

Authors:

Secondo Sonza

Helen P. Mutimer

Robert Oelrichs

Abstract

OBJECTIVE: To determine whether HIV-1 can be recovered from blood monocytes as well as resting, memory CD4 T lymphocytes of patients on highly active antiretroviral therapy (HAART) with undetectable plasma viraemia and whether infection is active or latent. DESIGN: Five patients with plasma HIV-1-RN...

Subject

Virology

Reverse transcriptase

Virus

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!