Treatment of polyarteritis nodosa and microscopic polyangiitis with poor prognosis factors: A prospective trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in sixty‐five patients

Guillevin, Loïc; Cohen, Pascal; Mahr, Alfred; Arène, Jean-Pierre; Mouthon, Luc; Puéchal, Xavier; Pertuiset, Édouard; Gilson, B; Hamidou, M.; Lanoux, Patricia; Bruet, A; Ruivard, M.; Vanhille, Philippe; Cordier, Jean‐François

doi:10.1002/art.10922

Public

Treatment of polyarteritis nodosa and microscopic polyangiitis with poor prognosis factors: A prospective trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in sixty‐five patients

Published in Arthritis Care & Research • Feb 7, 2003

Authors:

Loïc Guillevin

Pascal Cohen

Alfred Mahr

Abstract

OBJECTIVE: Because the optimal cyclophosphamide (CY) treatment duration for severe polyarteritis nodosa (PAN) without virus infection and microscopic polyangiitis (MPA) has not been established, we conducted a trial to compare the effectiveness of 6 versus 12 CY pulses given in combination with cort...

Subject

Microscopic polyangiitis

Medicine

Cyclophosphamide

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