Molecular analysis of chromosomh 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors

Josefa Bello, M.; Vaquero, Jesús; M. de Campos, José; Kusak, M.Elena; Luis Andrès Sarasa, José; S. Castresana, Javier; Pestaña, Ángel; A. Rey, Juan

doi:10.1002/ijc.2910570207

Public

Molecular analysis of chromosomh 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors

Published in International Journal of Cancer • Apr 15, 1994

Authors:

M. Josefa Bello

Jesús Vaquero

José M. de Campos

Abstract

Alterations of the short arm of chromosome 1 are recurrently found in cytogenetic analysis of malignant gliomas, and deletions of 1p36-p32 region characterize at least the higher-grade tumors, glioblastoma multiforme. Molecular analysis of tumor-derived and normal genomic DNA from 57 cases of glioma...

Subject

Oligodendroglial Tumor

Oligodendroglioma

Glioma

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