Targeting of Primary Breast Cancers and Metastases in a Transgenic Mouse Model Using Rationally Designed Multifunctional SPIONs

M. Kievit, Forrest; R. Stephen, Zachary; Veiseh, Omid; Arami, Hamed; Wang, Tingzhong; P. Lai, Vy; O. Park, James; G. Ellenbogen, Richard; L. Disis, Mary; Zhang, Miqin

doi:10.1021/nn205070h

Public

Targeting of Primary Breast Cancers and Metastases in a Transgenic Mouse Model Using Rationally Designed Multifunctional SPIONs

Published in ACS Nano • Feb 10, 2012

Authors:

Forrest M. Kievit

Zachary R. Stephen

Omid Veiseh

Abstract

Breast cancer remains one of the most prevalent and lethal malignancies in women. The inability to diagnose small volume metastases early has limited effective treatment of stage 4 breast cancer. Here we report the rational development and use of a multifunctional superparamagnetic iron oxide nanopa...

Subject

Breast cancer

In vivo

Cancer research

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