Bacillus Calmette-Guerin (BCG) immunotherapy for bladder cancer: current understanding and perspectives on engineered BCG vaccine.

Kawai, Koji; Miyazaki, Jun; Joraku, Akira; Nishiyama, Hiroyuki; Akaza, Hideyuki

doi:10.1111/cas.12075

Public

Bacillus Calmette-Guerin (BCG) immunotherapy for bladder cancer: current understanding and perspectives on engineered BCG vaccine.

Shared by NobleBlocks on Jan 1, 2013 • 12:00 AM UTC

Authors:

Koji Kawai

Jun Miyazaki

Akira Joraku

Abstract

Since the first report in 1976, accumulated clinical evidence has supported intravesical Bacillus Calmette-Guerin (BCG) therapy as one of the standard methods of management of intermediate- and high-risk non-muscle invasive bladder cancer. Despite its efficacy, intravesical BCG therapy is associated...

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