Combined Intravitreal Melphalan and Topotecan for Refractory or Recurrent Vitreous Seeding From Retinoblastoma

Ghassemi, Fariba; L. Shields, Carol; Ghadimi, Hadi; Khodabande, Alireza; Roohipoor, Ramak

doi:10.1001/jamaophthalmol.2014.414

Public

Combined Intravitreal Melphalan and Topotecan for Refractory or Recurrent Vitreous Seeding From Retinoblastoma

Published in JAMA Ophthalmology • May 1, 2014

Authors:

Fariba Ghassemi

Carol L. Shields

Hadi Ghadimi

Abstract

IMPORTANCE: Demonstrating the usefulness and complications of multiagent intravitreal chemotherapy is necessary for successful treatment in patients with recalcitrant vitreous seeding of retinoblastoma. OBJECTIVE: To determine the efficacy and complications of combined intravitreal chemotherapy (mel...

Subject

Medicine

Melphalan

Topotecan

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