Intracellular targeting of exoenzyme S of <i>Pseudomonas aeruginosa</i> via type III‐dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments

Frithz‐Lindsten, Elisabet; Du, Yidong; Rosqvist, Roland; Forsberg, Åke

doi:10.1046/j.1365-2958.1997.5411905.x

Public

Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III‐dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments

Published in Molecular Microbiology • Sep 1, 1997

Authors:

Elisabet Frithz‐Lindsten

Yidong Du

Roland Rosqvist

Abstract

Exoenzyme S (ExoS) is an ADP-ribosyltransferase secreted by the opportunistic pathogen Pseudomonas aeruginosa. The amino-terminal half of ExoS exhibits homology to the YopE cytotoxin of pathogenic Yersinia. Recently, YopE was found to be translocated into the host cell by a bacteria-cell contact-dep...

Subject

Biology

Phagocytosis

Intracellular

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