SLCO1B1 Genetic Variant Associated With Statin-Induced Myopathy: A Proof-of-Concept Study Using the Clinical Practice Research Datalink

F. Carr, Daniel; O’Meara, Helen; Jorgensen, Andrea; Campbell, Jennifer; Hobbs, Mark; P McCann, Gerry; van Staa, Tjeerd; Pirmohamed, Munir

doi:10.1038/clpt.2013.161

Public

SLCO1B1 Genetic Variant Associated With Statin-Induced Myopathy: A Proof-of-Concept Study Using the Clinical Practice Research Datalink

Published in Clinical Pharmacology & Therapeutics • Aug 13, 2013

Authors:

Daniel F. Carr

Helen O’Meara

Andrea Jorgensen

Abstract

This study aimed to determine whether patients with statin-induced myopathy could be identified using the United Kingdom Clinical Practice Research Datalink, whether DNA could be obtained, and whether previously reported associations of statin myopathy with the SLCO1B1 c.521T>C and COQ2 rs4693075 po...

Subject

SLCO1B1

Myopathy

Medicine

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