Molecular Detection of Micrometastatic Breast Cancer in Histopathology-Negative Axillary Lymph Nodes Correlates With Traditional Predictors of Prognosis

E. Gillanders, William; Mikhitarian, Kaidi; Hebert, Renée; D. Mauldin, Patrick; Y. Palesch, Yuko; Walters, Christian; M. Urist, Marshall; Bruce Mann, G.; M. Doherty, Gerard; M. Herrmann, Virginia; D. Hill, Arnold; Eremin, Oleg; El‐Sheemy, Mohamed; K. Orr, Richard; A. Valle, Alvaro; A. Henderson, Michael; L. DeWitty, Robert; L. Sugg, Sonia; R. Frykberg, Eric; A. Yeh, Karen; M. Bell, Richard; S. Metcalf, John; M. Elliott, Bruce; E. Brothers, Thomas; G. Robison, Jay; Mitas, Michael; J. Cole, David

doi:10.1097/01.sla.0000128687.59439.d6

Public

Molecular Detection of Micrometastatic Breast Cancer in Histopathology-Negative Axillary Lymph Nodes Correlates With Traditional Predictors of Prognosis

Published in Annals of Surgery • May 17, 2004

Authors:

William E. Gillanders

Kaidi Mikhitarian

Renée Hebert

Abstract

OBJECTIVE: We sought to establish the clinical relevance of micrometastatic disease detected by reverse transcription polymerase chain reaction (RT-PCR) in axillary lymph nodes (ALN) of breast cancer patients. BACKGROUND: The presence of ALN metastases remains one of the most valuable prognostic ind...

Subject

Medicine

Breast cancer

Histopathology

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