High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

Hee Kim, Jin; Rok Lee, Sang; Li, Li-Hua; Park, Hye‐Jeong; Park, Jeong-Hoh; Youl Lee, Kwang; Kim, Myeong‐Kyu; Ahn Shin, Boo; Choi, Seok‐Yong

doi:10.1371/journal.pone.0018556

Public

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

Published in PLoS ONE • Apr 29, 2011

Authors:

Jin Hee Kim

Sang Rok Lee

Li-Hua Li

Abstract

When expression of more than one gene is required in cells, bicistronic or multicistronic expression vectors have been used. Among various strategies employed to construct bicistronic or multicistronic vectors, an internal ribosomal entry site (IRES) has been widely used. Due to the large size and d...

Subject

Biology

Cleavage (geology)

Internal ribosome entry site

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