Hippocampal Atrophy Is Not a Major Determinant of Regional Hypometabolism in Temporal Lobe Epilepsy

J. O’Brien, Terence; R. Newton, M.; Cook, Mark; U. Berlangieri, Salvatore; Kilpatrick, Christine; Morris, Kevin; F. Berkovic, Samuel

doi:10.1111/j.1528-1157.1997.tb01080.x

Public

Hippocampal Atrophy Is Not a Major Determinant of Regional Hypometabolism in Temporal Lobe Epilepsy

Published in Epilepsia • Jan 1, 1997

Authors:

Terence J. O’Brien

M. R. Newton

Mark Cook

Abstract

PURPOSE: The pathophysiologic basis for the [18F]fluorodeoxyglucose positron-emission tomography (FDG-PET) temporal lobe hypometabolism in patients with hippocampal sclerosis (HS) is uncertain. We tested the hypothesis that hippocampal atrophy, which is strongly correlated with hippocampal cell loss...

Subject

Temporal lobe

Magnetic resonance imaging

Hippocampal formation

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