Maternal smoking during pregnancy is associated with epigenetic modifications of the brain‐derived neurotrophic factor‐6 exon in adolescent offspring

Toledo‐Rodriguez, Maria; Lotfipour, Shahrdad; Leonard, Gabriel; Perron, Michel; Richer, Louis; Veillette, Suzanne; Pausova, Zdenka; Paus, Tomáš

doi:10.1002/ajmg.b.31109

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Maternal smoking during pregnancy is associated with epigenetic modifications of the brain‐derived neurotrophic factor‐6 exon in adolescent offspring

Shared by NobleBlocks on Jun 25, 2010 • 12:00 AM UTC

Authors:

Maria Toledo‐Rodriguez

Shahrdad Lotfipour

Gabriel Leonard

Abstract

Abstract Prenatal exposure to maternal cigarette smoking (PEMCS) is associated with variations in brain and behavior in adolescence. Epigenetic mechanisms may mediate some of the consequences of PEMCS through methylation of deoxyribonucleic acid (DNA) in genes important for brain development, such a...

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