The Tutsi genocide and transgenerational transmission of maternal stress: epigenetics and biology of the HPA axis

Perroud, Nader; Rutembesa, Eugène; Paoloni‐Giacobino, Ariane; Mutabaruka, Jean; Mutesa, Léon; Stenz, Ludwig; Malafosse, Alain; Karege, Félicien

doi:10.3109/15622975.2013.866693

Public

The Tutsi genocide and transgenerational transmission of maternal stress: epigenetics and biology of the HPA axis

Published in The World Journal of Biological Psychiatry • Apr 1, 2014

Authors:

Nader Perroud

Eugène Rutembesa

Ariane Paoloni‐Giacobino

Abstract

OBJECTIVES: Transmission of parental post-traumatic stress disorder (PTSD) to offspring might be explained by transmission of epigenetic processes such as methylation status of the glucocorticoid receptor (GR) gene (NR3C1). METHODS: We investigated PTSD and depression severity, plasma cortisol, GR a...

Subject

Offspring

Genocide

Epigenetics

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