Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: Results from a multi‐center, randomized, active controlled trial

Trenkwalder, Claudia; Beneš, Heike; Grote, Ludger; Happe, Svenja; Högl, Birgit; Mathis, Johannes; Saletu‐Zyhlarz, G.; Kohnen, Ralf; study group, CALDIR

doi:10.1002/mds.21401

Public

Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: Results from a multi‐center, randomized, active controlled trial

Published in Movement Disorders • Feb 3, 2007

Authors:

Claudia Trenkwalder

Heike Beneš

Ludger Grote

Abstract

We report the first large-scale double-blind, randomly assigned study to compare two active dopaminergic therapies for Restless Legs Syndrome (RLS), the dopamine agonist cabergoline (CAB) and levodopa/benserazide (levodopa). Patients with idiopathic RLS were treated with fixed daily doses of 2 or 3 ...

Subject

Levodopa

Cabergoline

Restless legs syndrome

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