Rapamycin extends murine lifespan but has limited effects on aging

Neff, Frauke; Flores-Dominguez, Diana; Ryan, Devon; Horsch, Marion; Schröder, Susanne; Adler, Thure; Caminha Afonso, Luciana; Antonio Aguilar‐Pimentel, Juan; Becker, Lore; Garrett, Lillian; Hans, Wolfgang; M. Hettich, Moritz; Holtmeier, Richard; M. Hölter, Sabine; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Rácz, Ildikó; Rathkolb, Birgit; Rozman, Jan; Naton, Beatrix; Ordemann, Rainer; Adamski, Jerzy; Beckers, Johannes; Bekeredjian, Raffi; H. Busch, Dirk; Ehninger, Gerhard; Graw, Jochen; Höfler, Heinz; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Stypmann, Jörg; Wolf, Eckhard; Wurst, Wolfgang; Zimmer, Andreas; Fuchs, Helmut; Gailus‐Durner, Valérie; Hrabě de Angelis, Martin; Ehninger, Dan

doi:10.1172/jci67674

Public

Rapamycin extends murine lifespan but has limited effects on aging

Published in Journal of Clinical Investigation • Jul 24, 2013

Authors:

Frauke Neff

Diana Flores-Dominguez

Devon Ryan

Abstract

Aging is a major risk factor for a large number of disorders and functional impairments. Therapeutic targeting of the aging process may therefore represent an innovative strategy in the quest for novel and broadly effective treatments against age-related diseases. The recent report of lifespan exten...

Subject

Longevity

Biology

Cell biology

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