Human CSF-1: Molecular Cloning and Expression of 4-kb cDNA Encoding the Human Urinary Protein

Wong, Gordon; A. Temple, Patricia; C. Leary, Anne; Witek-Giannotti, J; Yang, Yu‐Chung; Ciarletta, A.; P. Chung, Margaret; E. Murtha, Patricia; Kriz, Ronald; J. Kaufman, Randal; R. Ferenz, Catherine; S. Sibley, Barbara; J. Turner, Katherine; M. Hewick, Rodney; C. Clark, Steven; Yanai, Nobuya; Yokota, Hajime; Yamada, Muneo; Saito, Minoru; Motoyoshi, Kazuo; Takaku, Fumimaro

doi:10.1126/science.3493529

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Human CSF-1: Molecular Cloning and Expression of 4-kb cDNA Encoding the Human Urinary Protein

Published in Science • Mar 20, 1987

Authors:

Gordon Wong

Patricia A. Temple

Anne C. Leary

Abstract

A 4-kilobase complementary DNA (cDNA) encoding human macrophage-specific colony-stimulating factor (CSF-1) was isolated. When introduced into mammalian cells, this cDNA directs the expression of CSF-1 that is structurally and functionally indistinguishable from the natural human urinary CSF-1. Direc...

Subject

Complementary DNA

Molecular cloning

Biology

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