The ‘Refoldability’ of Selected Proteins in Ionic Liquids as a Stabilization Criterion, Leading to a Conjecture on Biogenesis

The folding of proteins is usually studied in dilute aqueous solutions of controlled pH, but it has recently been demonstrated that reversible unfolding can occur in other media. Particular stability is conferred on the protein (folded or unfolded) when the process occurs in ‘protic ionic liquids’ (... View More