Differential Uptake of Functionalized Polystyrene Nanoparticles by Human Macrophages and a Monocytic Cell Line

Lunov, Oleg; Syrovets, Tatiana; Loos, Cornelia; Beil, Johanna; Delacher, Michael; Tron, Kyrylo; Ulrich Nienhaus, G.; Musyanovych, Anna; Mailänder, Volker; Landfester, Katharina; Simmet, Thomas

doi:10.1021/nn2000756

Public

Differential Uptake of Functionalized Polystyrene Nanoparticles by Human Macrophages and a Monocytic Cell Line

Published in ACS Nano • Feb 23, 2011

Authors:

Oleg Lunov

Tatiana Syrovets

Cornelia Loos

Abstract

Tumor cell lines are often used as models for the study of nanoparticle-cell interactions. Here we demonstrate that carboxy (PS-COOH) and amino functionalized (PS-NH2) polystyrene nanoparticles of ∼100 nm in diameter are internalized by human macrophages, by undifferentiated and by PMA-differentiate...

Subject

Pinocytosis

Endocytosis

Phagocytosis

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!