Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

Haferlach, Torsten; Nagata, Yasunobu; Grossmann, Vera; Okuno, Yusuke; Bacher, Ulrike; Nagae, Genta; Schnittger, Susanne; Sanada, Masashi; Kon, Ayana; Alpermann, Tamara; Yoshida, Kenichi; Roller, Andreas; Nadarajah, Niroshan; Shiraishi, Yuichi; Shiozawa, Yusuke; Chiba, Kenichi; Tanaka, Hiroko; Phillip Koeffler, H.; Klein, H-U; Dugas, Martin; Aburatani, Hiroyuki; Kohlmann, Alexander; Miyano, Satoru; Haferlach, Claudia; Kern, Wolfgang; Ogawa, Seishi

doi:10.1038/leu.2013.336

Public

Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

Published in Leukemia • Nov 13, 2013

Authors:

Torsten Haferlach

Yasunobu Nagata

Vera Grossmann

Abstract

High-throughput DNA sequencing significantly contributed to diagnosis and prognostication in patients with myelodysplastic syndromes (MDS). We determined the biological and prognostic significance of genetic aberrations in MDS. In total, 944 patients with various MDS subtypes were screened for known...

Subject

Myelodysplastic syndromes

Gene

Oncology

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