Hypoxia‐enhanced wound‐healing function of adipose‐derived stem cells: Increase in stem cell proliferation and up‐regulation of VEGF and bFGF

Young Lee, Eun; Xia, Ying; Kim, Won‐Serk; Hee Kim, Myoung; Kim, Tae‐Hwan; Jeung Kim, Kea; Park, Byung‐Soon; Sung, Jong‐Hyuk

doi:10.1111/j.1524-475x.2009.00499.x

Public

Hypoxia‐enhanced wound‐healing function of adipose‐derived stem cells: Increase in stem cell proliferation and up‐regulation of VEGF and bFGF

Published in Wound Repair and Regeneration • Jul 1, 2009

Authors:

Eun Young Lee

Ying Xia

Won‐Serk Kim

Abstract

Adipose-derived stem cells (ADSCs) have been shown to induce wound-healing effects. Because inflammation near the wound area induces oxygen deficiency, it is interesting to elucidate the effect of hypoxia on the function of ADSCs. In this work, we asked: (1) does hypoxia alter the wound-healing func...

Subject

Wound healing

Hypoxia (environmental)

Vascular endothelial growth factor

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