Interleukin‐1β induces cytosolic phospholipase a<sub>2</sub> and prostaglandin h synthase in rheumatoid synovial fibroblasts

I. Hulkower, Keren; J. Wertheimer, Stanley; Levin, Wayne; W. Coffey, John; M. Anderson, Celia; Chen, Ting; L. DeWitt, David; M. Crowl, Robert; C. Hope, William; W. Morgan, Douglas

doi:10.1002/art.1780370508

Public

Interleukin‐1β induces cytosolic phospholipase a2 and prostaglandin h synthase in rheumatoid synovial fibroblasts

Published in Arthritis & Rheumatism • May 1, 1994

Authors:

Keren I. Hulkower

Stanley J. Wertheimer

Wayne Levin

Abstract

OBJECTIVE: In order to investigate potential regulatory mechanisms for the increased production of prostaglandin E2 (PGE2) in interleukin-1 beta (IL-1 beta)-stimulated rheumatoid synovial fibroblasts (RSF), this study examined the induction of phospholipase A2 (PLA2) and prostaglandin H synthase (PG...

Subject

Phospholipase A

Prostaglandin

Internal medicine

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