A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1

E. Clark, Dawn; K. Smith, S.; He, Yulong; Day, Kate; R. Licence, Diana; N. Corps, Anthony; Lammoglia, Rosemarie; Stephen Charnock‐Jones, D.

doi:10.1095/biolreprod59.6.1540

Public

A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1

Published in Biology of Reproduction • Dec 1, 1998

Authors:

Dawn E. Clark

S. K. Smith

Yulong He

Abstract

Vascular endothelial growth factor (VEGF) is a potent secreted factor that promotes angiogenesis and maintains the integrity of the endothelium. Levels of VEGF are increased in many tumors and are elevated in women with pre-eclampsia, a serious disease of pregnancy. Here we show by in situ hybridiza...

Subject

Biology

Vascular endothelial growth factor

Angiogenesis

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!