IGF2 DNA methylation is a modulator of newborn’s fetal growth and development

St‐Pierre, Julie; Hivert, Marie‐France; Perron, Patrice; Poirier, Paul; Guay, Simon‐Pierre; Brisson, Diane; Bouchard, Luigi

doi:10.4161/epi.21855

Public

IGF2 DNA methylation is a modulator of newborn’s fetal growth and development

Published in Epigenetics • Sep 6, 2012

Authors:

Julie St‐Pierre

Marie‐France Hivert

Patrice Perron

Abstract

The insulin-like growth factor 2 (IGF2) gene, located within a cluster of imprinted genes on chromosome 11p15, encodes a fetal and placental growth factor affecting birth weight. DNA methylation variability at the IGF2 gene locus has been previously reported but its consequences on fetal growth and ...

Subject

Biology

DNA methylation

Genomic imprinting

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