Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.

DH, O'Connor; BR, Mothe; JT, Weinfurter; S, Fuenger; WM, Rehrauer; P, Jing; RR, Rudersdorf; ME, Liebl; K, Krebs; J, Vasquez; E, Dodds; J, Loffredo; S, Martin; AB, McDermott; TM, Allen; C, Wang; GG, Doxiadis; DC, Montefiori; A, Hughes; DR, Burton; DB, Allison; SM, Wolinsky; R, Bontrop; LJ, Picker; DI, Watkins

doi:10.1128/jvi.77.16.9029-9040.2003

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Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.

Shared by NobleBlocks on Aug 1, 2003 • 12:00 AM UTC

Authors:

O'Connor DH

Mothe BR

Weinfurter JT

Abstract

Certain major histocompatibility complex class I (MHC-I) alleles are associated with delayed disease progression in individuals infected with human immunodeficiency virus (HIV) and in macaques infected with simian immunodeficiency virus (SIV). However, little is known about the influence of these MH...

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