Major Histocompatibility Complex Class I Alleles Associated with Slow Simian Immunodeficiency Virus Disease Progression Bind Epitopes Recognized by Dominant Acute-Phase Cytotoxic-T-Lymphocyte Responses

H. O’Connor, David; R. Mothé, Bianca; T. Weinfurter, Jason; Fuenger, Sarah; M. Rehrauer, William; Jing, Peicheng; R. Rudersdorf, Richard; Emanuel Liebl, Max; Krebs, Kendall; Vasquez, Joshua; Dodds, Elizabeth; T. Loffredo, John; R. Martin, Sarah; B. McDermott, Adrian; M. Allen, Todd; Wang, Chenxi; G. M. Doxiadis, Gaby; C. Montefiori, David; L. Hughes, Austin; R. Burton, Dennis; B. Allison, David; M. Wolinsky, Steven; E. Bontrop, Ronald; J. Picker, Louis; I. Watkins, David

doi:10.1128/jvi.77.16.9029-9040.2003

Public

Major Histocompatibility Complex Class I Alleles Associated with Slow Simian Immunodeficiency Virus Disease Progression Bind Epitopes Recognized by Dominant Acute-Phase Cytotoxic-T-Lymphocyte Responses

Published in Journal of Virology • Jul 28, 2003

Authors:

David H. O’Connor

Bianca R. Mothé

Jason T. Weinfurter

Abstract

Certain major histocompatibility complex class I (MHC-I) alleles are associated with delayed disease progression in individuals infected with human immunodeficiency virus (HIV) and in macaques infected with simian immunodeficiency virus (SIV). However, little is known about the influence of these MH...

Subject

Biology

Virology

Cytotoxic T cell

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