Aerosolized Amiloride: Dose Effect on Nasal Bioelectric Properties, Pharmacokinetics, and Effect on Sputum Expectoration in Patients with Cystic Fibrosis

Hofmann, Thomas; SENIER, IVONNE; BITTNER, PETER; Hüls, G; Schwandt, Hans-Joachim; Lindemann, H.

doi:10.1089/jam.1997.10.147

Public

Aerosolized Amiloride: Dose Effect on Nasal Bioelectric Properties, Pharmacokinetics, and Effect on Sputum Expectoration in Patients with Cystic Fibrosis

Published in Journal of Aerosol Medicine • Jan 1, 1997

Authors:

Thomas Hofmann

IVONNE SENIER

PETER BITTNER

Abstract

Aerosolized amiloride normalizes the excessive sodium absorption cystic fibrosis (CF) respiratory epithelium. The aims of this study were to assess the dose-effect relationship and the duration for which amiloride inhibits Na+ transport, to determine acute and chronic pharmacokinetics, and to test t...

Subject

Amiloride

Inhalation

Cystic fibrosis

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!