Treatment of Septic Shock with Human Monoclonal Antibody HA-1A

V. McCloskey, Richard; C. Straube, Richard; Sanders, Corazon; M. Smith, Susan; R. Smith, Craig; CHESS Trial Study Group., and

doi:10.7326/0003-4819-121-1-199407010-00001

Public

Treatment of Septic Shock with Human Monoclonal Antibody HA-1A

Published in Annals of Internal Medicine • Jul 1, 1994

Authors:

Richard V. McCloskey

Richard C. Straube

Corazon Sanders

Abstract

OBJECTIVE: To compare the effectiveness of 100 mg of HA-1A and placebo in reducing the 14-day all-cause mortality rate in patients with septic shock and gram-negative bacteremia in the Centocor: HA-1A Efficacy in Septic Shock (CHESS) trial, and to assess the safety of 100 mg of HA-1A given to patien...

Subject

Medicine

Septic shock

Monoclonal antibody

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