Plasma Metabolomic Profiles Reflective of Glucose Homeostasis in Non-Diabetic and Type 2 Diabetic Obese African-American Women

Fiehn, Oliver; Timothy Garvey, W.; W. Newman, John; H. Lok, Kerry; L. Hoppel, Charles; H. Adams, Sean

doi:10.1371/journal.pone.0015234

Public

Plasma Metabolomic Profiles Reflective of Glucose Homeostasis in Non-Diabetic and Type 2 Diabetic Obese African-American Women

Published in PLoS ONE • Dec 10, 2010

Authors:

Oliver Fiehn

W. Timothy Garvey

John W. Newman

Abstract

Insulin resistance progressing to type 2 diabetes mellitus (T2DM) is marked by a broad perturbation of macronutrient intermediary metabolism. Understanding the biochemical networks that underlie metabolic homeostasis and how they associate with insulin action will help unravel diabetes etiology and ...

Subject

Internal medicine

Insulin resistance

Endocrinology

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