Low‐level increases in serum C‐reactive protein are present in early osteoarthritis of the knee and predict progressive disease

D. Spector, T.; J. Hart, D.; Nandra, D.; V. Doyle, D.; Mackillop, N.; R. Gallimore, J.; B. Pepys, M.

doi:10.1002/art.1780400419

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Low‐level increases in serum C‐reactive protein are present in early osteoarthritis of the knee and predict progressive disease

Shared by NobleBlocks on Apr 1, 1997 • 12:00 AM UTC

Authors:

T. D. Spector

D. J. Hart

D. Nandra

Abstract

Abstract Objective. To examine the role of low‐grade inflammation in the etiology and progression of early osteoarthritis (OA) of the knee. Methods. We used a new, high‐sensitivity, automated monoclonal antibody immunoassay for the classic acute‐phase protein, C‐reactive protein (CRP), in serum. Ant...

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