Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

Kuchenbaecker, Karoline; L. Neuhausen, Susan; E. Robson, Mark; Barrowdale, Daniel; McGuffog, Lesley; Marie Mulligan, Anna; L. Andrulis, Irene; B. Spurdle, Amanda; K. Schmidt, Marjanka; K. Schmutzler, Rita; Engel, Christoph; Wappenschmidt, Barbara; Nevanlinna, Heli; Thomassen, Mads; C. Southey, Melissa; Radice, Paolo; J. Ramus, Susan; M. Domchek, Susan; L. Nathanson, Katherine; Lee, Andrew; Healey, Sue; L. Nussbaum, Robert; R. Rebbeck, Timothy; Arun, Banu; A. James, Paul; Y. Karlan, Beth; Lester, Jenny; Cass, Ilana; Cancer Family Registry, Breast; Beth Terry, Mary; B Daly, Mary; E. Goldgar, David; S. Buys, Saundra; Janavičius, Ramūnas; Tihomirova, Laima; Tung, Nadine; M. Dorfling, Cecilia; J. van Rensburg, Elizabeth; Steele, Linda; van Overeem Hansen, Thomas; Ejlertsen, Bent; Gerdes, Anne‐Marie; C. Nielsen, Finn; Dennis, Joe; Cunningham, Julie; N. Hart, Steven; L. Slager, Susan; Osório, Ana; Benítez, Javier; Durán, M.; N. Weitzel, Jeffrey; Tafur, Isaac; Hander, Mary; Peterlongo, Paolo; Manoukian, Siranoush; Peissel, Bernard; Roversi, Gaia; Scuvera, Giulietta; Bonanni, Bernardo; Mariani, P.; Volorio, Sara; Dolcetti, Riccardo; Varesco, Liliana; Papi, Laura; Grazia Tibiletti, Maria; Giannini, Giuseppe; Fostira, Florentia; Konstantopoulou, Irene; Garber, Judy; Hamann, Ute; Donaldson, Alan; Brewer, Carole; Foo, Claire; Gareth Evans, D.; Frost, Debra; Eccles, Diana; Douglas, Fiona; F. Brady, Angela; Cook, Jackie; Tischkowitz, Marc; Adlard, Julian; Barwell, Julian; Ong, Kai-Ren; Walker, Lisa; Izatt, Louise; Side, Lucy; J. Kennedy, Michael; T. Rogers, Mark; Porteous, Mary; J. Morrison, Patrick; Platte, Radka; Eeles, Ros; Davidson, Rosemarie; Hodgson, Shirley; Ellis, Steve; K. Godwin, Andrew; Rhiem, Kerstin; Meindl, Alfons; Ditsch, Nina; Arnold, Norbert; Plendl, Hansjoerg; Niederacher, Dieter; Sutter, Christian; Steinemann, Doris; Bogdanova-Markov, Nadja; Kast, Karin; Varon-Mateeva, Raymonda; Wang-Gohrke, Shan; Gehrig, Andrea; Markiefka, Birgid; Buecher, Bruno; Lefol, Cédrick; Stoppa-Lyonnet, Dominique; Rouleau, Étienne; Prieur, Fabienne; Damiola, Francesca; Barjhoux, Laure; Faivre, Laurence; Longy, Michel; Sévenet, Nicolas; M. Sinilnikova, Olga; Mazoyer, Sylvie; Bonadona, Valérie; Caux-Moncoutier, Virginie; Isaacs, Claudine; Van Maerken, Tom; Claes, Kathleen; Piedmonte, Marion; Andrews, Lesley; L. Hays, John; C. Rodriguez, Gustavo; Caldes, Trinidad; de la Hoya, Miguel; Khan, Sofia; B.L. Hogervorst, Frans; M. Aalfs, Cora; Lange, J.; Meijers‐Heijboer, Hanne; H. van der Hout, Annemarie; Wijnen, Juul; van Roozendaal, KEP; R. Mensenkamp, Arjen; M van den Ouweland, A; HM van Deurzen, Carolien; B. van der Luijt, Rob; Olah, Edith; Dı́ez, Orland; Lázaro, Conxi; Blanco, Ignacio; Teulé, Àlex; Menéndez, Mireia; Jakubowska, Anna; Lubiński, Jan; Cybulski, Cezary; Gronwald, Jacek; Jaworska-Bieniek, Katarzyna; Durda, Katarzyna; Arason, Aðalgeir; Maugard, Christine; Soucy, Penny; Montagna, Marco; Agata, Simona; R. Teixeira, Manuel; Olswold, Curtis; Lindor, Noralane; Shane Pankratz, V.; Hallberg, Emily; Wang, Xianshu; I. Szabo, Csilla; Vijai, Joseph; Jacobs, Lauren; Corines, Marina; Lincoln, Anne; Berger, Andreas; Fink-Retter, Anneliese; F. Singer, Christian; Rappaport, Christine; Gschwantler Kaulich, Daphne; Pfeiler, Georg; Tea, Muy-Kheng; M. Phelan, Catherine; L Mai, Phuong; H. Greene, Mark; Rennert, Gad; N. Imyanitov, Evgeny; Glendon, Gord; Ewart Toland, Amanda; Bojesen, Anders; Søkilde Pedersen, Inge; Birk Jensen, Uffe; A. Caligo, Maria; Friedman, Eitan; Berger, Raanan; Laitman, Yael; Rantala, Johanna; Arver, Brita; Loman, Niklas; Borg, Åke; Ehrencrona, Hans; I. Olopade, Olufunmilayo; Simard, Jacques; F. Easton, Douglas; Chenevix‐Trench, Georgia; Offit, Kenneth; J. Couch, Fergus; C. Antoniou, Antonis; Study, EMBRACE; Study Collaborators, GEMO; , HEBON; Investigators, KConFab

doi:10.1186/s13058-014-0492-9

Public

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

Published in Breast Cancer Research • Dec 30, 2014

Authors:

Karoline Kuchenbaecker

Susan L. Neuhausen

Mark E. Robson

Abstract

INTRODUCTION: More than 70 common alleles are known to be involved in breast cancer (BC) susceptibility, and several exhibit significant heterogeneity in their associations with different BC subtypes. Although there are differences in the association patterns between BRCA1 and BRCA2 mutation carrier...

Subject

Breast cancer

Surgical oncology

Medicine

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