Micro<scp>RNA</scp>‐122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting <scp>Wnt/β</scp>‐catenin pathway

Xu, Jie; Zhu, Xiuming; Wu, Lingjiao; Yang, Rong; Yang, Zeran; Wang, Qiangfeng; Wu, Fusheng

doi:10.1111/j.1478-3231.2011.02750.x

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MicroRNA‐122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/β‐catenin pathway

Shared by NobleBlocks on Jan 26, 2012 • 12:00 AM UTC

Authors:

Jie Xu

Xiuming Zhu

Lingjiao Wu

Abstract

Abstract Aims To validate whether the anti‐cancer effect of micro RNA ‐122 ( miR ‐122) on hepatocellular carcinoma ( HCC ) is mediated through regulating Wnt/β ‐catenin signalling pathways. Methods The expression levels of miR ‐122 in HCC tissues and varied hepatoma cells were quantified by real‐tim...

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