Independently Evolved Virulence Effectors Converge onto Hubs in a Plant Immune System Network

Shahid Mukhtar, M.; Carvunis, Anne‐Ruxandra; Dreze, Matija; Epple, Petra; Steinbrenner, Jens; D. Moore, Jonathan; Taşan, Murat; Galli, Mary; Hao, Tong; T. Nishimura, Marc; Pevzner, Samuel; E. Donovan, Susan; Ghamsari, Lila; Santhanam, Balaji; Romero, Viviana; M. Poulin, Matthew; Gebreab, Fana; J. Gutierrez, Bryan; Tam, Stanley; Monachello, Dario; Boxem, Mike; J. Harbort, Christopher; A. McDonald, Nathan; Gai, Lantian; Chen, Huaming; He, Yijian; Vandenhaute, Jean; P. Roth, Frederick; E. Hill, David; R. Ecker, Joseph; Vidal, Marc; Beynon, Jim; Falter‐Braun, Pascal; L. Dangl, Jeffery

doi:10.1126/science.1203659

Public

Independently Evolved Virulence Effectors Converge onto Hubs in a Plant Immune System Network

Published in Science • Jul 28, 2011

Authors:

M. Shahid Mukhtar

Anne‐Ruxandra Carvunis

Matija Dreze

Abstract

Plants generate effective responses to infection by recognizing both conserved and variable pathogen-encoded molecules. Pathogens deploy virulence effector proteins into host cells, where they interact physically with host proteins to modulate defense. We generated an interaction network of plant-pa...

Subject

Virulence

Effector

Immune system

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