Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: A morphological and ERG study

Gargini, Claudia; Terzibasi Tozzini, Eva; Mazzoni, Francesca; Strettoi, Enrica

doi:10.1002/cne.21144

Public

Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: A morphological and ERG study

Published in The Journal of Comparative Neurology • Nov 16, 2006

Authors:

Claudia Gargini

Eva Terzibasi Tozzini

Francesca Mazzoni

Abstract

Retinal degeneration 10 (rd10) mice are a model of autosomal recessive retinitis pigmentosa (RP), identified by Chang et al. in 2002 (Vision Res. 42:517-525). These mice carry a spontaneous mutation of the rod-phosphodiesterase (PDE) gene, leading to a rod degeneration that starts around P18. Later,...

Subject

Retinitis pigmentosa

Retinal degeneration

Retina

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