Type 5 17β-Hydroxysteroid Dehydrogenase (AKR1C3) Contributes to Testosterone Production in the Adrenal Reticularis

Nakamura, Yasuhiro; J. Hornsby, Peter; R. Casson, Peter; Morimoto, Ryo; Satoh, Fumitoshi; Xing, Yewei; R. Kennedy, Michael; Sasano, Hironobu; E. Rainey, William

doi:10.1210/jc.2008-2374

Public

Type 5 17β-Hydroxysteroid Dehydrogenase (AKR1C3) Contributes to Testosterone Production in the Adrenal Reticularis

Published in The Journal of Clinical Endocrinology & Metabolism • Apr 1, 2009

Authors:

Yasuhiro Nakamura

Peter J. Hornsby

Peter R. Casson

Abstract

CONTEXT: The human adrenal gland produces small amounts of testosterone that are increased under pathological conditions. However, the mechanisms through which the adrenal gland produces testosterone are poorly defined. OBJECTIVE: Our objective was to define the role of type 5 17beta-hydroxysteroid ...

Subject

Zona reticularis

Adrenal gland

Endocrinology

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