Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE).

JF, Viallard; JL, Pellegrin; V, Ranchin; T, Schaeverbeke; J, Dehais; M, Longy-Boursier; JM, Ragnaud; B, Leng; JF, Moreau

doi:10.1046/j.1365-2249.1999.00766.x

Public

Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE).

Shared by NobleBlocks on Jan 1, 1999 • 12:00 AM UTC

Authors:

Viallard JF

Pellegrin JL

Ranchin V

Abstract

We investigated the production of IL-2, IFN-gamma, IL-10 and IL-4 by PBMC from 24 patients with SLE and 10 healthy individuals. Basal and mitogen-stimulated (lipopolysaccharide and phytohaemagglutinin (LPS + PHA)) cytokine production was determined in a whole blood assay (WBA). Supernatants were col...

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