Label-Free Protein Biosensor Based on Aptamer-Modified Carbon Nanotube Field-Effect Transistors

Maehashi, Kenzo; Katsura, Taiji; Kerman, Kağan; Takamura, Yuzuru; Matsumoto, Kazuhiko; Tamiya, Eiichi

doi:10.1021/ac060830g

Public

Label-Free Protein Biosensor Based on Aptamer-Modified Carbon Nanotube Field-Effect Transistors

Published in Analytical Chemistry • Dec 9, 2006

Authors:

Kenzo Maehashi

Taiji Katsura

Kağan Kerman

Abstract

We have fabricated label-free protein biosensors based on aptamer-modified carbon nanotube field-effect transistors (CNT-FETs) for the detection of immunoglobulin E (IgE). After the covalent immobilization of 5'-amino-modified 45-mer aptamers on the CNT channels, the electrical properties of the CNT...

Subject

Aptamer

Biosensor

Carbon nanotube

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