Prospective evaluation of a chamomile mouthwash for prevention of 5-FU-induced oral mucositis

Fidler, Pat; L. Loprinzi, Charles; R. OʼFallon, Judith; M. Leitch, John; K. Lee, Jeraldine; L. Hayes, Debra; J. Novotny, Paul; Clemens-Schutjer, Danette; Bartel, J; C. Michalak, John

doi:10.1002/(sici)1097-0142(19960201)77:3<522::aid-cncr14>3.0.co;2-6

Public

Prospective evaluation of a chamomile mouthwash for prevention of 5-FU-induced oral mucositis

Published in Cancer • Feb 1, 1996

Authors:

Pat Fidler

Charles L. Loprinzi

Judith R. OʼFallon

Abstract

BACKGROUND: Stomatitis has been found to be a major dose-limiting toxicity from bolus 5-fluorouracil-based (5-FU) chemotherapy regimens, despite the use of oral cryotherapy. Pursuant to preliminary data which suggested that a chamomile mouthwash might ameliorate this toxicity, a prospective trial wa...

Subject

Medicine

Mucositis

Stomatitis

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