Quantifying Residual HIV-1 Replication in Patients Receiving Combination Antiretroviral Therapy

Zhang, Linqi; Ramratnam, Bharat; Tenner‐Racz, Klara; He, Yuxian; Vesanen, Mika; R. Lewin, Sharon; H. Talal, Andrew; Rácz, Paul; S. Perelson, Alan; Korber, Bette; Markowitz, Martin; Guo, Yong; Durán, Margarita; Hurley, Arlene; Tsay, John; Huang, Yu‐Ching; Wang, Chia-Ching; D. Ho, David

doi:10.1056/nejm199905273402101

Public

Quantifying Residual HIV-1 Replication in Patients Receiving Combination Antiretroviral Therapy

Published in New England Journal of Medicine • May 27, 1999

Authors:

Linqi Zhang

Bharat Ramratnam

Klara Tenner‐Racz

Abstract

BACKGROUND: In patients infected with human immunodeficiency virus type 1 (HIV-1), combination antiretroviral therapy can result in sustained suppression of plasma levels of the virus. However, replication-competent virus can still be recovered from latently infected resting memory CD4 lymphocytes; ...

Subject

Viral replication

Virology

Virus

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