Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones

Kon, Elizaveta; Muraglia, Anita; Corsi, Alessandro; Bianco, P.; Marcacci, Maurilio; Martín, Iván; Boyde, A.; Ruspantini, Irene; Chistolini, P.; Rocca, M.; Giardino, Roberto; Cancedda, Ranieri; Quarto, Rodolfo

doi:10.1002/(sici)1097-4636(20000305)49:3<328::aid-jbm5>3.0.co;2-q

Public

Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones

Published in Journal of Biomedical Materials Research • Mar 5, 2000

Authors:

Elizaveta Kon

Anita Muraglia

Alessandro Corsi

Abstract

The ability of marrow-derived osteoprogenitor cells to promote repair of critical-size tibial gaps upon autologous transplantation on a hydroxyapatite ceramic (HAC) carrier was tested in a sheep model. Conditions for in vitro expansion of sheep bone marrow stromal cells (BMSC) were established and t...

Subject

Materials science

Stromal cell

Bone marrow

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