The EML4‐ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild‐type EGFR and KRAS

Wing‐Sze Wong, Daisy; Lai‐Han Leung, Elaine; Kam‐Ting So, Kimpton; Yee San Tam, Issan; Dart‐Loon Sihoe, Alan; Cheng, Lik‐Cheung; Ho, Kwok‐Keung; S. K. Au, Joseph; Chung, Lap‐Ping; Pik Wong, Maria

doi:10.1002/cncr.24181

Public

The EML4‐ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild‐type EGFR and KRAS

Published in Cancer • Jan 23, 2009

Authors:

Daisy Wing‐Sze Wong

Elaine Lai‐Han Leung

Kimpton Kam‐Ting So

Abstract

BACKGROUND: The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23) recently was identified in nonsmall cell lung cancer (NSCLC). The authors of this study investigated the frequency, genetic and c...

Subject

Anaplastic lymphoma kinase

KRAS

Cancer research

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