Inhibition of the production and effects of interleukins‐1 and tumor necrosis factor α in rheumatoid arthritis

This review has summarized information published over the last 5 years on the presence and pathophysiologic role of IL-1 and TNF alpha in RA. The evidence to date shows that 5 of 6 criteria for identifying mediators of tissue damage in human autoimmune diseases are satisfied (Table 1). The last crit... View More