An Antimicrobial Peptide, Magainin 2, Induced Rapid Flip-Flop of Phospholipids Coupled with Pore Formation and Peptide Translocation

Matsuzaki, Katsumi; Murase, Osamu; Fujii, Nobutaka; Miyajima, Koichiro

doi:10.1021/bi960016v

Public

An Antimicrobial Peptide, Magainin 2, Induced Rapid Flip-Flop of Phospholipids Coupled with Pore Formation and Peptide Translocation

Published in Biochemistry • Jan 1, 1996

Authors:

Katsumi Matsuzaki

Osamu Murase

Nobutaka Fujii

Abstract

The effect of an antimicrobial peptide, magainin 2, on the flip-flop rates of phospholipids was investigated by use of fluorescent lipids, i.e., anionic N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)dipalmitoyl-L-alpha- phosphatidylethanolamine (NBD-PE), 1-oleoyl-2-[12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)ami...

Subject

Peptide

Magainin

Chemistry

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!