Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies

Race, Esther; M. Dam, Elizabeth; Obry, Véronique; Paulous, Sylvie; Clavel, François

doi:10.1097/00002030-199910220-00008

Public

Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies

Published in AIDS • Oct 1, 1999

Authors:

Esther Race

Elizabeth M. Dam

Véronique Obry

Abstract

OBJECTIVE: To assess the patterns of HIV phenotypic cross-resistance to protease inhibitors (PI) in patients experiencing viral load rebound on combination therapy including a PI. METHODS: Phenotypic analysis of sensitivity to indinavir, nelfinavir, saquinavir, ritonavir and amprenavir was carried o...

Subject

Saquinavir

Amprenavir

Nelfinavir

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