The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method

IntHout, Joanna; P. A. Ioannidis, John; F. Borm, George

doi:10.1186/1471-2288-14-25

Public

The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method

Published in BMC Medical Research Methodology • Feb 18, 2014

Authors:

Joanna IntHout

John P. A. Ioannidis

George F. Borm

Abstract

BACKGROUND: The DerSimonian and Laird approach (DL) is widely used for random effects meta-analysis, but this often results in inappropriate type I error rates. The method described by Hartung, Knapp, Sidik and Jonkman (HKSJ) is known to perform better when trials of similar size are combined. Howev...

Subject

Meta-analysis

Statistics

Sample size determination

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