Molecular Cloning of a Gene Encoding a New Type of Metalloproteinase-disintegrin Family Protein with Thrombospondin Motifs as an Inflammation Associated Gene

Kuno, Kouji; Kanada, Naomi; Nakashima, Emi; Fujiki, Fujio; Ichimura, Fujio; Matsushima, Kouji

doi:10.1074/jbc.272.1.556

Public

Molecular Cloning of a Gene Encoding a New Type of Metalloproteinase-disintegrin Family Protein with Thrombospondin Motifs as an Inflammation Associated Gene

Published in Journal of Biological Chemistry • Jan 1, 1997

Authors:

Kouji Kuno

Naomi Kanada

Emi Nakashima

Abstract

A cellular disintegrin and metalloproteinase (ADAM) is a new family of genes with structural homology to the snake venom metalloproteinases and disintegrins. We screened genes which were selectively expressed in the cachexigenic colon 26 adenocarcinoma subline in vivo. It was found that one novel cD...

Subject

Disintegrin

Thrombospondin

Biology

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