White matter hyperintensities and normal-appearing white matter integrity in the aging brain

Muñoz Maniega, Susana; C. Valdés Hernández, Maria; D. Clayden, Jonathan; A. Royle, Natalie; Murray, Catherine; Morris, Zoë; S. Aribisala, Benjamin; J. Gow, Alan; M. Starr, John; E. Bastin, Mark; J. Deary, Ian; M. Wardlaw, Joanna

doi:10.1016/j.neurobiolaging.2014.07.048

Public

White matter hyperintensities and normal-appearing white matter integrity in the aging brain

Published in Neurobiology of Aging • Oct 13, 2014

Authors:

Susana Muñoz Maniega

Maria C. Valdés Hernández

Jonathan D. Clayden

Abstract

White matter hyperintensities (WMH) of presumed vascular origin are a common finding in brain magnetic resonance imaging of older individuals and contribute to cognitive and functional decline. It is unknown how WMH form, although white matter degeneration is characterized pathologically by demyelin...

Subject

Hyperintensity

White matter

Neuroscience

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