Collaborative interplay between FGF-2 and VEGF-C promotes lymphangiogenesis and metastasis

Cao, Renhai; Ji, Hong; Feng, Ninghan; Zhang, Yin; Yang, Xiaojuan; Andersson, Patrik; Sun, Yuping; Tritsaris, Katerina; Jón Hansen, Anker; Dissing, Steen; Cao, Yihai

doi:10.1073/pnas.1208324109

Public

Collaborative interplay between FGF-2 and VEGF-C promotes lymphangiogenesis and metastasis

Published in Proceedings of the National Academy of Sciences • Sep 11, 2012

Authors:

Renhai Cao

Hong Ji

Ninghan Feng

Abstract

Interplay between various lymphangiogenic factors in promoting lymphangiogenesis and lymphatic metastasis remains poorly understood. Here we show that FGF-2 and VEGF-C, two lymphangiogenic factors, collaboratively promote angiogenesis and lymphangiogenesis in the tumor microenvironment, leading to w...

Subject

Lymphangiogenesis

Angiogenesis

Cancer research

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!